Solutions

Low cost, rapid whole-genome sequencing

Crucial for continued vigilance against new SARS-CoV-2 variants

Non-Diagnostic Sequencing for Surveillance Use

In addition to diagnostic COVID-19 PCR testing, PRL performs non-diagnostic, whole genome sequencing to detect and track SARS-CoV-2 variants in real time and inform both public and private health responses.

First in NY to Discover Beta and Omicron Variants

PRL’s large-scale genome sequencing workflow can identify new and potentially dangerous mutations. We were the first to discover the Beta and Omicron variants in New York State in 2021.

Public Health Data

PRL’s rapid sequencing workflow has had a profound impact on epidemiologic surveillance capabilities to inform local and national public health responses. We have uploaded about 50,000 sequences to GISAID, the global access genomic data database, as of March 2022.

Sequencing Capacity

While PRL provides 80 percent of the sequencing capacity in New York and 2 percent of the world’s capacity, we have not reached our maximum sequencing potential and are able to take on more samples.

SARS-CoV-2 Variant Tracker

Variant prevalence over time from PRL samples

Resource Links

Why utilize our sequencing service?

Fast and affordable variant identification through viral genome sequencing

Mitigate the Spread

Our non-diagnostic advanced sequencing workflow can identify circulating variants at a surveillance-level, providing critical public health information in shaping mitigation and response.

Seamless Integration

PRL has integrated a large-scale, COVID testing pipeline for direct sequencing of positive samples for variant detection.

Low Cost Burden

Our whole-genome sequencing service is a fraction of the cost compared to market leaders. Contact us to discuss cost for your particular project.

Quick Turnaround Time

On average, sequencing results are delivered within 3-7 days.

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Learn how you can benefit from PRL's advanced sequencing workflow

FAQs

What sequencing services does PRL offer?

PRL offers non-diagnostic, whole-genome sequencing of SARS-CoV-2 viral RNA. Results are to be used for research, investigational, or surveillance use only, and are not to be used to provide individual diagnosis. Customers can either sequence a percentage of the samples sent in for PRL's SCV2 PCR workflow (biosurveillance), or specify particular samples to be sequenced (STAT).

What is the sequencing technology?

PRL employs Illumina’s amplicon-based whole genome sequencing workflow.

What is shown on the sequencing report?

The PRL whole-genome sequencing report is completed using reference-based alignment against the genome of the first ancestral SARS-CoV-2 variant. Pangolin lineages are reported.

How do I order sequencing services?

Submit a quote request for pricing. Contact our team.

How much does STAT sequencing cost?

STAT sequencing starts at $160 per sample.

What is the average turnaround time for STAT sequencing?

PRL will provide whole-genome sequencing result reports for STAT samples within 72 hours of STAT sample accessioning, not including weekends. STAT samples received by PRL prior to 10 a.m. on business days will be accessioned the day of receipt. STAT samples received after 10 a.m. or on non-business days will be accessioned on the following business day.

What sample types are accepted for STAT sequencing?

Samples accepted are nasopharyngeal and anterior nares swabs in viral transport media or DNA/RNA shield. Saliva samples in DNA/RNA shield are accepted. We also accept extracted RNA.

What is the sample volume required for STAT sequencing?

A minimum of 200 µL sample volume is required.

What is the storage requirement for STAT samples prior to sequencing?

If feasible, STAT swab samples should be sent to PRL as soon as possible. STAT swab samples can be stored in 4°C for up to 3 days. For long-term storage, the sample should be stored in -80°C. Inform PRL whether the sample has already been heat-inactivated. All samples should be shipped on dry ice.

What is the regulatory status of PRL’s sequencing service?

Sequencing data provided by PRL is for research, investigational, or surveillance use only, and is not to be reported to patients for diagnostic purposes. PRL’s sequencing service has not been reviewed by the FDA/federal regulators or New York State regulators. Sequencing services may be conducted in a facility that is not certified under the Clinical Laboratory Improvement Amendments ("CLIA").

Which PRL lab performs sequencing service?

Currently, sequencing is performed in PRL’s research and development laboratory in Long Island City, NY, which can accept samples from all 50 states.

Is PRL CLIA certified?

PRL has 3 CLIA-certified labs - PRL NY (New York, NY): 33D2196459, PRL DC (Rockville, MD): 21D2215498, PRL OC (Irvine, CA): 05D2230382

Where can I find PRL?

PRL has labs in Long Island City, NY, Irvine, CA and Rockville, MD. PRL is exploring opening additional labs across the country.